37/2022

Wykład laureata Nagrody Nobla w Instytucie Nenckiego

Z przyjemnością zapraszamy Państwa na wyjątkowe seminarium Instytutu Nenckiego, którego gościem będzie Prof. Dr. Tom Sudhof – Profesor na Uniwersytecie Stanforda oraz laureat Nagrody Nobla w dziedzinie fizjologii lub medycyny w 2013 roku.

Seminarium odbędzie się 15 września 2022 o 17:00 CET w Instytucie Nenckiego oraz w formie online.

Serdecznie zapraszamy.

Invitation for a lecture of Prof. Thomas Graf

Dear All

I would like to invite you to a seminar that we are organizing on the next Tuesday, September 13th at 3pm in the CN Lecture Hall at the Nencki Institute.

We will host prof Thomas Graf, head of the Gene Regulation, Stem Cells and Cancer Laboratory at the Center for Genomic Regulation, Barcelona. Prof. Graf will give a lecture entitled: Mechanisms of transcription factor-induced cell fate conversions

Abstract

A central problem in developmental biology is how cell fates are specified. During differentiation cells are exposed to various signals from their microenvironment that ultimately result in the activation and/or repression of lineage instructive transcription factors (LiTFs). Defined combinations of LiTFs then regulate the expression of cell type specific programs, but how these factors rewire the cell’s transcriptome and epigenome during cell fate induction is still not completely understood. Our lab has been studying LiTF- induced cell fate conversions using C/EBPa as a paradigm. I will discuss how the factor converts B cells into macrophages and how the same factor also plays a role in enhancing Yamanaka factor-induced B cell reprogramming into iPS cells. Our results illuminate cell fate specification mechanisms during hematopoietic differentiation and early embryo development.

The lecture will be followed by a get together reception.

With best regards
Aleksandra Pękowska

Invitation for a lecture of Prof. Martin Vingron

Dear All

I would like to invite to you a lecture that we organize on the 12th of September at 2pm in the CN Hall at the Nencki Institute. We will host prof. Martin Vingron, head of the Transcriptional Regulation Group and the Scientific Director of the Max Planck Institute for Molecular Genetics in Berlin.

Prof. Vingron will give a lecture entitled: Machine learning in gene regulation: simple methods and complex data

Abstract
This presentation will summarize a few projects where machine learning methods are being employed to unravel gene regulatory mechanisms. The challenge lies in the combination of DNA sequence information with functional measurements on the epigenetic state of the chromatin in order to rationalize in which cellular state a gene gets activated. Time permitting, I will include some philosophical remarks on the importance of the choice of positive and, especially, negative training data.

The lecture will be followed by a get together reception.

With best regards
Aleksandra Pękowska

Obrona rozprawy doktorskiej mgr Palomy Alvarez Suarez

4 października 2022 r. o godz. 12:00 w sali im. Jerzego  Konorskiego na II piętrze budynku głównego, odbędzie się publiczna obrona rozprawy doktorskiej na stopień doktora nauk ścisłych i przyrodniczych w dyscyplinie nauki biologiczne mgr Palomy Alvarez Suarez pt. „Drebrin and myosin VI: Cytoskeletal regulators of the development of the postsynaptic machinery at the murine neuromuscular junction”.

Promotorem jest  prof. dr hab. Maria Jolanta Rędowicz,  promotorem pomocniczym dr Marta Gawor

Recenzentami pracy są: prof. dr hab. Małgorzata Daczewska z Uniwersytetu Wrocławskiego, prof. dr hab. Zbigniew Madeja z Uniwersytetu Jagiellońskiego oraz prof. dr hab. Elżbieta Pyza z Uniwersytetu Jagiellońskiego

Link do streszczenia i recenzji: https://cloud.nencki.gov.pl/d/23662a5181/

Obrona rozprawy doktorskiej mgr Agaty Poświaty

3 października 2022 r. o godz. 12:00 w sali im. Jerzego  Konorskiego na II piętrze budynku głównego, odbędzie się  publiczna obrona rozprawy doktorskiej na stopień doktora nauk ścisłych i przyrodniczych w dyscyplinie nauki biologiczne mgr Agaty Poświaty pt.“The interactome of AXL receptor provides insights into its biological roles and interacellular trafficking”.

Promotorem jest prof. dr hab. Marta Miączyńska, promotorem pomocniczym dr Daria Zdżalik-Bielecka.

Recenzentami pracy są: Dr hab. Joanna Kamińska z Instytutu Biochemii i Biofizyki PAN w Warszawie, prof. dr hab. Zbigniew Madeja z Uniwersytetu Jagiellońskiego oraz Dr hab. Paweł Niewiadomski z Centrum Nowych Technologii UW.

Link do streszczenia i recenzji: https://cloud.nencki.gov.pl/d/6cac664da3/

Obrona rozprawy doktorskiej mgr. Oresta V. Matveichuka

W imieniu Rady Naukowej Instytutu uprzejmie zapraszamy na obronę pracy doktorskiej mgr. Oresta V. Matveichuka pt.“The role of flotillins and their S-palmitoylation in LPS-induced signaling”,

Promotorem jest  prof. dr hab. Katarzyna Kwiatkowska.
Recenzentami pracy są: prof. dr hab. Jolanta Jura z Uniwersytetu Jagiellońskiego oraz  dr hab. Sylwia Wrotek, prof. UMK z Uniwersytetu Mikołaja Kopernika w Toruniu

Obrona odbędzie się  19 września 2022 r. o godzinie 12:00 w sali im. Jerzego  Konorskiego na II piętrze budynku głównego.

W załączeniu link do streszczenia i recenzji: https://cloud.nencki.gov.pl/d/801209e877/

Euro-BioImaging

Dear Euro-BioImaging Colleagues and Friends, 

Here are some career advancement opportunities, workshops and events from the Euro-BioImaging community that we are pleased to share with you.

Best wishes from the Euro-BioImaging Hub Team

Training & Workshops:

eRImote Workshops (online) – September 21 & 22 
The eRImote Project is organizing many interesting Workshops this Fall! On September 21 & 22, the topic is Remote training for RI users and staff & User interactions and networking in remote/digital service provision. We hope you will join!
Full information: https://erimote.eu/news-and-events

eRImote Workshops (online) – October 24 & 25
On October 24-25, topics include Remote operations of RI services and Data and access security.  Don’t miss this exciting opportunity to exchange with other core facility staff, RI partners and industry and learn from each other.
Full information: https://erimote.eu/news-and-events

Career advancement opportunities:

Research Associate in Bio-Image Analysis, Sheffield University, Sheffield, UK
Alice Pyne’s team at Sheffield University, UK, is hiring a new bioimage analyst within the UKRI Future Leaders Fellow programme grant “Unravelling the invisible complexities of the genome”. The project aims to develop new bioimage analysis tools for the Atomic Force Microscopy field, and to apply these to a number of exciting collaborative projects across the UK and US with impact in gene therapies, cancer and ageing.
Apply by September 11: https://pyne-lab.uk/pdra-image-analysis

Bioimage Analyst and Research Software Engineer, Human Technopole, Milan, Italy
Florian Jug’s Group at the Human Technopole is hiring a Bioimage Analyst and Research Software Engineer to work on the AI4LIFE project (https://www.eurobioimaging.eu/news/proud-to-be-part-of-the-ai4life-project/) that will provide sustainable, intuitive, and highest quality research services and infrastructures that will enable life scientists to exploit machine learning to improve the utility and interpretability of image data, the key to fast-paced progress in biomedical research.
Apply by September 13: https://careers.humantechnopole.it/o/bioimage-analyst-and-research-software-engineer-ai4life-project-florian-jug-group

Software Engineer Research, Erasmus MC, Rotterdam, the Netherlands
Our  Population Imaging Infrastructure Node, based at Erasmus MC, is hiring a Software Engineer to work on developments within the EuCanImage project to build a secure and federated imaging platform for next-generation artificial intelligence and precision medicine in oncology.
Apply by September 29: https://www.werkenbijerasmusmc.nl/en/vacancy/76401/software-engineer-research-34.29.22.tda

Conferences & Events: 

Global BioImaging Exchange of Experience VII, Montevideo, Uruguay & ONLINE – September 14-16
The annual conference organized in collaboration with Latin America BioImaging is in hybrid format this year. It represents an open forum for discussion and new ideas, where imaging facility managers and technical staff, scientists, science policy officers, vendors and funders from around the globe will come together to discuss how Imaging can contribute to sustainable development.
More information: https://globalbioimaging.org/exchange-of-experience/exchange-of-experience-vii

PET is Wonderful 2022, Edinburgh, Scotland with LIVE streaming – September 27 & 28  
Don’t miss the annual PET is Wonderful meeting, held online or in-person this year. Check out the excellent scientific programme and learn more about the Chan Zuckerberg – PET is Wonderful summer scholarship programme for those wanting to learn more about PET imaging.
Late abstract submission until September 16: https://petiswonderful.org/pet-is-wonderful-2022/

COMULIS Conference, Nicosia, Cyprus – September 21-22
This in person event will emphasize correlative imaging methods (CMI) able to capture the dynamics of life, spanning the whole range from molecular resolution to imaging whole organisms. The conference program offers an attractive combination of oral presentations and posters with selected poster presenters, invited for short flash talks. It will also provide excellent opportunities for discussions and informal gatherings. Industry talks are included.
Registration is FREE:
https://www.comulis.eu/comulis-conference-2022

4th volume EM Town Hall Meeting, ONLINE – October 5
We are excited to announce that registration is now open for the 4th volume EM Town Hall Meeting, which will take place on Wednesday 5th October from 09:00-17:00 BST/ 10:00 – 18:00 CEST on Zoom.
Program coming soon on the Volume EM website.
Register here:
https://forms.gle/bbuk95MGZdvWmTXL6

Euro-BioImaging User Forum: Fighting infectious diseases, ONLINE – October 6th @ 14:00 CEST
This event will highlight the importance of cutting-edge imaging technologies in support of pandemic preparedness, finding treatments and understanding the underlying biology of infectious agents. We will showcase the specific expertise available at our Nodes across Europe through case studies presented in tandem with the research community.

Keynote speakers include:

• Anne-Marie Chacko, Duke-NUS Medical School, “A role for in vivo imaging in infectious disease: driving drug discovery by monitoring treatment response”
• Cristina Risco Ortiz, Cell Structure Laboratory, CNB-CSIC, “Imaging viral infections: Identifying new targets for antiviral treatments”

Register here: https://www.eurobioimaging.eu/news/join-us-for-the-fourth-euro-bioimaging-user-forum-fighting-infectious-diseases/

Live webinar: Better understand cell structure and mechanisms with Amira Software (Industry event)
September 29, 2022 | Virtual Event
Session 1: ASIA/EMEA | 9:30 a.m. CEST | 5:30 p.m. KST
Session 2: EMEA/AMERICAS | 4:30 p.m. CEST | 8:30 a.m. PST

Thermo Scientific™ Amira™ Software provides a comprehensive array of tools for the flexible and accurate analysis of time series data of cellular mechanisms. It enables researchers to perform dedicated segmentation workflows on their intra- and intercellular images and apply powerful automated object tracking solutions.

Attend this webinar to learn how Amira Software can help you:

• Accelerate subcellular (membrane, organelle) detection and segmentation from Electron Microscopy (TEM) data using a range of readily available tools, including 3D Deep Learning model training.
• Analyze multichannel fluorescence endothelial cell culture data by performing fast and effective cleaning, segmentation, volume colocalization and neighbor cell proximity.
• Extract complex information in 3D such as detection, segmentation and penetration of cancer or immune cells to manage multichannel High Content Screening multi-well images of organoid models.
• Quickly convert, visualize and accurately process large (~100GB) multi-channel and time series light sheet tissue imaging data.

The webinar will last approximately 25 minutes + Q&A session.

Register here: https://ter.li/njybpm