11 marca 2022 r. o godz. 12:00 odbędzie się on-line publiczna obrona rozprawy doktorskiej na stopień doktora nauk ścisłych i przyrodniczych w dyscyplinie nauki biologiczne mgr. Michała Szczepanika pt. “Neural Correlates of Emotional Contagion in Humans: Familiarity Between Participants Does Not Enhance Transmission of Fear”

Promotor: dr hab. Ewelina Knapska, prof Instytutu Nenckiego PAN
Promotor pomocniczy: dr Marek Wypych
Recenzenci: prof. dr hab. Przemysław Bąbel, dr hab. Monika Wróbel, prof. UŁ, prof. Claus Lamm

Link do obrony: https://zoom.us/j/93994520821?pwd=K0RQWnNMbys5cGd5TnFJa1lDTlR6QT09

Link do streszczenia i recenzji: https://cloud.nencki.gov.pl/d/c69b11b468/

You are invited to a Zoom webinar
When: Mar 11, 2022 12:00 AM Warsaw
Topic: Obrona pracy doktorskiej mgr. Michała Szczepanika

Please click the link below to join the webinar:

https://zoom.us/j/93994520821?pwd=K0RQWnNMbys5cGd5TnFJa1lDTlR6QT09

Passcode: 130381
Or One tap mobile:
Poland: +48223987356,,93994520821#,,,,*130381# or +48223065342,,93994520821#,,,,*130381#

Or Telephone:
Dial(for higher quality, dial a number based on your current location):
Poland: +48 22 398 7356 or +48 22 306 5342 or +48 22 307 3488
Webinar ID: 939 9452 0821
Passcode: 130381
International numbers available: https://zoom.us/u/adYvdpGOPZ

Dear All

It is my great pleasure to invite you to the Nencki Institute Seminar which will take place online next Thursday, February the 17^th, at 3 pm.

We will host Prof. Rafał Bartoszewski from the Department of Biology and Pharmaceutical Botany at the Medical University of Gdansk, who will give a lecture entitled Modulators or power switches in cellular stress responses: miRNA lessons from hypoxia and UPR.

Abstract

miRNAs are genome-encoded small RNAs that mediate post-transcriptional silencing of mRNA targets in a sequence-dependent fashion. Notably, miRNA are an important component of dynamic cellular stress responses, allowing cells to effectively counteract diverse stresses and ensuring the cell’s survival or alternatively eliminating damaged or unwanted cells. During the presentation, I will discuss the miRNA involvement in adaptive response to hypoxia as well as their role in unfolded protein response ^{1, 2}. I will focus on our experimental results of integration of miRNA levels changes with the main transcriptomic regulators of both of these stress responses including HIF-1, HIF-2 and XBP1 as well as their functional consequences ^{3, 4, 5, 6}.

References

1. Bartoszewski R, et al.Primary endothelial cell-specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia.FASEB J 33, 7929-7941 (2019).
2. Bartoszewski R, et al.The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.J Biol Chem 286, 41862-41870 (2011).
3. Bartoszewska S,et al.. miR-34c-5p modulates X-box-binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response. FASEB J 33, 11541-11554 (2019).
4. Bartoszewska S, et al.The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1alpha expression in human endothelial cells through a negative feedback loop.FASEB J 29, 1467-1479 (2015).
5. Janaszak-Jasiecka A, et al.eNOS expression and NO release during hypoxia is inhibited by miR-200b in human endothelial cells.Angiogenesis 21, 711-724 (2018).
6. Gebert M, et al.Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor.Cell Mol Life Sci 78, 7061-7080 (2021).

Please use the following link:

https://zoom.us/j/98222231110?pwd=Uyt6Q29BaGlLSXBsUnJRQnpWc0pJZz09 

Meeting ID: 982 2223 1110
Passcode: 795926

Best regards,
Aleksandra Pękowska

Polskie Towarzystwo Etologiczne zaprasza na wykład mgr. Mateusza Kosteckiego (Pracownia Neurobiologii Emocji Instytutu Biologii Doświadczalnej im. Marcelego Nenckiego PAN, Warszawa) „Etologia, neuroetologia, etologia obliczeniowa – czyli dokąd zmierzamy”.

Wykład online odbędzie się na platformie Webex, w czwartek 17 lutego 2022 r., o godz. 18.00. Możliwość zalogowania się będzie otwarta od godz. 17.15.

Link do spotkania: https://coape.webex.com/coape/onstage/g.php?MTID=ead57cda23c0730ce1969606cf8701258

Szanowni Państwo,

Zapraszamy do wysłuchania kolejnego wykładu w ramach cyklu „Nowe Oblicza Biochemii 2022” organizowanego przez Polskie Towarzystwo Biochemiczne. Webinar on-line odbędzie się 24 lutego 2022 r., o godz. 13:00.

Wykład (po polsku) pt. „Aldolaza i fruktozo bisfosfataza – „moonlighting proteins”; wielofunkcyjność to nie praca po godzinach”, wygłosi prof. dr hab. Dariusz Rakus (Zakład Fizjologii i Neurobiologii Molekularnej, Uniwersytet Wrocławski)

Osoby zainteresowane wykładem prosimy o rejestrację na platformie ZOOM WEBINAR:
https://zoom.us/webinar/register/WN_E6HRQPwWQk2p65BHc4K0WQ