Szanowni Państwo,

Życzymy, aby nadchodzące Święta Wielkanocne były radosne, pełne harmonii i nadziei na lepsze dni.

Dyrekcja Instytutu Nenckiego

Dr Agnieszka Dębska z Pracowni Neurobiologii Procesów Językowych otrzymała finansowanie Fundacji Kościuszkowskiej na odbycie 5-miesięcznego stażu w grupie prof. Jamesa Bootha na Uniwersytecie Vanderbilt w Nashville, Tennessee. W ramach projektu badane będą relacje między obszarami mózgu odpowiedzialnymi za przetwarzanie fonologiczne i ortograficzne w podłużnym schemacie eksperymentalnym.

Prof. Booth i jego współpracownicy mają szerokie doświadczenie badawcze w rozumieniu mózgowych podstaw rozwoju czytania. W ciągu ostatniej dekady stworzyli fundament badań nad mózgowym podłożem procesów przetwarzania ortograficznego i mowy.

Projekt przyczyni się do lepszego zrozumienia neurobiologii procesu nabywania, ważnej z perspektywy społecznej i edukacyjnej, umiejętności czytania.

Dear All

it is my pleasure to inform you that this Thursday, April 8th, at 3pm, Prof. Alexej Verkhratsky from the University of Manchester will be our next guest speaker at the Nencki Institute seminar series.

Professor Verkhratsky, one of the leaders in cell glial biology, his work has shaped this field and allowed us to understand better the processes leading to neurodegeneration. He has also contributed immensely towards our understanding of the role of calcium as a messenger in the cell. Prof Verkhratsky will give a lecture entitled „Principles of astrogliopathology”

Abstract

Astroglia represent a main element in the maintenance of homeostasis and providing defense to the brain. Dysfunction of astrocytes underlies many, if not all, neurological disorders. General astrogliopathy is evident in diametrically opposing morpho-functional changes in astrocytes, i.e. their reactive hypertrophy or atrophy with asthenia. These complex plastic changes underlie pathophysiology of all neurological disorders including neuropsychiatric and neurodegenerative diseases. In particular, astrocytes regulate glutamatergic transmission through the removal of glutamate from the extracellular space and by supplying neurones with glutamine. Glutamatergic transmission is generally believed to be significantly impaired in the contexts of all major neuropsychiatric diseases. In most of these neuropsychiatric diseases astrocytes show signs of degeneration and atrophy, which is likely to be translated into reduced homeostatic capabilities. Astroglial glutamate uptake/release and glutamate homeostasis are affected in all forms of psychiatric and neurodegenerative disorders and represent a common mechanism underlying neurotransmission dysbalance, aberrant synaptic connectivity and overall failure on information processing by neuronal networks, thus leading to cognitive and behavioural deficits. In Alzheimer’s disease (AD) astrocytes undergo complex and multifaceted metamorphoses ranging from atrophy with loss of function to reactive astrogliosis with hypertrophy. Astroglial asthenia underlies reduced homeostatic support and neuroprotection that may account for impaired synaptic transmission and neuronal demise. Reactive astrogliosis which mainly develops in astrocytes associated with senile plaques is prominent at the early to moderate stages of AD manifested by mild cognitive impairment; down-regulation of astrogliosis (reflecting astroglial paralysis) is associated with late stages of the disease characterised by severe dementia. Cell-specific therapies aimed at boosting astroglial supportive and defensive capabilities and preventing astroglial paralysis may offer new directions in preventing, arresting or even curing AD-linked neurodegeneration.

https://zoom.us/j/91262243656?pwd=eUt5WGg1OHlrb1NuV0RQQmtPRUl2Zz09
Meeting ID: 912 6224 3656
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Best regards,
Aleksandra Pękowska

16 kwietnia 2021 r. o godz. 12:00 odbędzie się on-line publiczna obrona rozprawy doktorskiej na stopień doktora nauk ścisłych i przyrodniczych w dyscyplinie nauki biologiczne mgr Anny Banaszkiewicz pt. „Neuroplasticity and sign language: Insights from longitudinal and cross-sectional multimodal studies of hearing learners and deaf signers”

Promotor: dr hab. Artur Marchewka, prof. Instytutu Nenckiego PAN
Recenzenci: prof. dr hab. Grzegorz Króliczak, dr hab. Zofia Wodniecka-Chlipalska, prof. UJ

Link do obrony: https://zoom.us/j/93256823532?pwd=WmErQ1E0ZEhuYjBqZ2ZNOWl6TjEvdz09

Link do streszczenia i recenzji: https://cloud.nencki.gov.pl/d/ce2582b4c3/

Zoom Nencki is inviting you to a scheduled Zoom meeting.
Topic: Zaproszenie na obronę mgr Anny Banaszkiewicz
Time: Apr 16, 2021 11:30 AM Warsaw
Join Zoom Meeting https://zoom.us/j/93256823532?pwd=WmErQ1E0ZEhuYjBqZ2ZNOWl6TjEvdz09

Meeting ID: 932 5682 3532
Passcode: 507666
One tap mobile
+48223065342,,93256823532#,,,,*507666# Poland
+48223073488,,93256823532#,,,,*507666# Poland

Dial by your location
+48 22 306 5342 Poland
+48 22 307 3488 Poland
+48 22 398 7356 Poland
Meeting ID: 932 5682 3532
Passcode: 507666
Find your local number: https://zoom.us/u/abIBK9TZ9z

Dear All,

Nencki Institute as a representative of SPARK Poland within the SPARK Europe would like to cordially invite you to participate in the next webinar of European SPARKs joint series on April 7th, 16-17 CET.

During the webinar titled “Regulation, do we really need it? Critical considerations for successful drug development” we will try to answer the question of why there are so many various laws, rules standards, directives, and guidelines in the pharmaceutical industry. The speaker who will share with us his experience is Ilana Schumacher, a clinical pharmacist, specialized in quality assurance in pharmaceuticals, medical devices, and combination products development.

The series of webinars is open for all students and employees of SPARK associated organizations (Nencki Institute PAS and International Institute of Molecular and Cell Biology in Warsaw).

Registration to the webinar is required in advance. Please register at: https://us02web.zoom.us/meeting/register/tZIucOuvqjMoE9TrxlVyvt9lgpGH_cRc72YV

latest on April 6th. With later registrations access cannot be guaranteed. There are a limited number of places available and they are filled in in the order of registration.

As a reminder, webinars will take place biweekly on Wednesday at 16 -17 CET and will cover topics from design thinking to challenges in selling complex high-tech products from top-quality speakers around Europe and the US.

Best regards,
Paulina Santus